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Targeting Protein–Protein Interactions: Suppression of Stat3 Dimerization with Rationally Designed Small‐Molecule,Nonpeptidic SH2 Domain Binders |
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| Authors: | Patrick T. Gunning Dr. Matthew P. Glenn Dr. Khandaker A. Z. Siddiquee Dr. William P. Katt Eric Masson Dr. Saïd M. Sebti Prof. James Turkson Prof. Andrew D. Hamilton Prof. |
| Affiliation: | 1. Department of Chemistry, Yale University, P.?O. Box 208017, New Haven, CT 06520‐8107 (USA), Fax: (+1)?203‐432‐3221;2. Department of Molecular Biology and Microbiology, University of Central Florida, Orlando, FL 32826 (USA);3. Drug Discovery Program, H. Lee Moffitt Cancer Center and Research Institute, Department of Oncology and Department of Biochemistry and Molecular Biology, University of South Florida, Tampa, FL 33612 (USA) |
| Abstract: | |
| Keywords: | antitumor agents molecular recognition protein– protein interactions small molecules Stat3 |