| 改性卵磷脂的微乳化性研究 |
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| 引用本文： | 蒋笃孝,彭一鸣,宋龄瑛.改性卵磷脂的微乳化性研究[J].食品科学,2004,25(4):28-32. |
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| 作者姓名： | 蒋笃孝 彭一鸣 宋龄瑛 |
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| 作者单位： | 广州暨南大学化学系，广州大学化学系 |
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| 基金项目： | 国务院侨办重点学科基金项目(93A119) |
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| 摘 要： | 对人豆卵磷脂进行羟氯化改性,以此为表面活性剂,醇为助表面活性剂。采用三相图形式和电导率来进行跟踪检测。对室温下改性卵磷脂各体统中微乳区域的形成以及微乳液理化性质随系统中各组分的变化情况进行了研究。结果发现醇中碳的数目为3时,微乳区域最大;电导率与微乳化有关。改性后的大豆卵磷脂比改性前的效果有明显的改善,羟氯化改性卵磷脂为不错的制备药物载体。
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| 关 键 词： | 大豆卵磷脂 改性 微乳 助表面活性剂 相图 电导率 |
| 文章编号： | 1002-6630(2004)04-0028-05 |
Investigation of Microemulsions of Modified Lecithin |
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| JIANG Du-xiao,PENG Yi-ming,SONG Ling-ying.Investigation of Microemulsions of Modified Lecithin[J].Food Science,2004,25(4):28-32. |
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| Authors: | JIANG Du-xiao PENG Yi-ming SONG Ling-ying |
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| Affiliation: | 1.Departmt of Chemistry, Jinan University;2.Department of Chemistry,Guangzhou University |
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| Abstract: | The formation of microemulsion phase for systems containing modified soybean lecithin and the effect of formulationvariables on the physical-chemistry characterization of micioemuision were studied. Soybean lecithin was modified byhydroxychloride in NaClO. Then it was used as surfactant and several short chain alcohols and investigated as cosurfactant.Investigation of the phase and conductance for the microemulsion showed that if C≈3,it could hold the biggest microemulsion.And conductivity would change with water. Modified soybean lecithin was found more effective than lecithin. It was used betterin drug delivery system. And it could be used in reduced amount in cholesterin. |
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| Keywords: | soybean lecithin modification microemulsion cosurfactant pseudo-ternary diagrams conductivity |
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