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Ethnic differences in women with HIV infection in Britain and Ireland. The study group for the mrc collaborative study of HIV infection in women |
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| Authors: | J Anderson R Melville DJ Jeffries J Norman J Welch D Graham M Fadojutimi G Forster M Phillips K Sampson V Kitchen C Wells G Byrne DE Mercey E Allason-Jones L Campbell R French H Woronowski A Griffioen JM Stephenson AN Phillips R Keenlyside AM Johnson S Barton V Chard S Harindra |
| Affiliation: | Centre for Human Biology, University of Leeds, W. Yorkshire, U.K. |
| Abstract: | Homeobox (hox) genes are of considerable importance in the formation of the body axis of invertebrates and vertebrates. The postulation of a hox-code (i.e. the simultaneous activity of a certain subset of hox genes) for structures at different metameric levels and which differ from each other in shape suggests a relationship between hox-code and shape, which is reinforced by the possibility of homeotic transformation when the hox-code is changed experimentally. This paper considers the possible nature of such a relationship between the hox genes governing vertebral formation in the upper part of the mouse vertebral column and the shape of the adult vertebrae formed in this region. |
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