| Synthesis and radioiodinated labeling of p—iodophenyl pentadecanoic acid |
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| 引用本文： | WuChun－Ying JiShu－Ren 等.Synthesis and radioiodinated labeling of p—iodophenyl pentadecanoic acid[J].核技术(英文版),1998,9(4):246-250. |
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| 作者姓名： | WuChun－Ying JiShu－Ren |
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| 作者单位： | [1]JiangsuInstituteofNuclearMedicine,StateKeyLaboratoryofNuclearMdicine,Wuxi214063 [2]JiangsuInstituteofNuc,StateKeyLaboratoryofNuclearMdicine,Wuxi214063 |
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| 摘 要： | A new method for the preparation of p-iodophenyl pentadecanoic acid(IPPA) has been developed.The synthesis are described,and physical properties of IPPA are characterized by IR,1HNMR,elementary analysis and MS.^125I-IPPA can be easily prepared by two methods:direct labeling and solid-phase iodo-exchange labeling,and the yields of labeling are 80% and 65%,respectively,The radiochemical purities are higher than 98% after being extracted with chloroform and hexane.
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| 关 键 词： | 放射性碘示踪 对十五烷酸碘苯酯 合成 |
Synthesis and radioiodinated labeling of p-iodophenyl pentadecanoic acid |
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| Wu Chun-Ying, Ji Shu-Ren, Fang Ping.Synthesis and radioiodinated labeling of p-iodophenyl pentadecanoic acid[J].Nuclear Science and Techniques,1998,9(4):246-250. |
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| Authors: | Wu Chun-Ying Ji Shu-Ren Fang Ping |
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| Abstract: | A new method for tile preparation of p-iodophenyl pentadecanoic acid (IPPA)has been developed. The synthesis are described, and physical properties of IPPA are characterized by IR, 1HNMR, elementary analysis and MS. 125I-IPPA can be easily prepared bytwo methods: direct labeling and solid-phase iodo-exchange labeling, and the yields of labelingare 80% and 65%, respectively. The radiochcnrical purities are higher than 98% after beingextracted with chloroform and he-cane. |
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| Keywords: | Hiodophenyl pentadecanoic acid Fatty acid Synthesis ~(125)I-IPPA ~(125)I-labeling |
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