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姜黄素结构修饰的研究进展
引用本文:张荣凯,曲建强.姜黄素结构修饰的研究进展[J].化学工业与工程,2011,28(5):61-67.
作者姓名:张荣凯  曲建强
作者单位:天津大学理学院,天津,300072
基金项目:天津大学自主创新基金资助项目(60302020)
摘    要:对姜黄素衍生物类药物的结构修饰进行归类,探讨了姜黄素衍生物的生物活性与化学结构的关系,分析了姜黄素衍生物中化学基团对生物活性的影响,为以后合成具有高效专一的生物活性姜黄素衍生物提供依据。

关 键 词:姜黄素衍生物  抗氧化  抗癌  抗炎

Progress in Structure Modification of Curcumin
ZHANG Rong-kai,QU Jian-qiang.Progress in Structure Modification of Curcumin[J].Chemical Industry and Engineering,2011,28(5):61-67.
Authors:ZHANG Rong-kai  QU Jian-qiang
Affiliation:ZHANG Rong-kai,QU Jian-qiang(School of Science,Tianjin University,Tianjin,30072,China)
Abstract:The curcumin derivatives were summarized and classified according to their different structures.The relationships of their structure and activity were discussed.The influences of the substitute groups on the biological activities were proposed.Those would provide assistances for the subsequent synthesis of curcumin derivatives with high and specific biological activity.
Keywords:curcumin derivatives  antioxidation  antitumor  anti-inflammatory  
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