| 山柰素对照品的制备研究 |
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| 引用本文： | 侯红瑞,陈玲,王春晓,孙国勇,张小凤. 山柰素对照品的制备研究[J]. 当代化工, 2017, 46(2) |
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| 作者姓名： | 侯红瑞 陈玲 王春晓 孙国勇 张小凤 |
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| 作者单位： | 1. 茂名职业技术学院,广东茂名,525000;2. 华南理工大学食品科学与工程学院,广东广州,510640 |
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| 基金项目： | 茂名市科技计划项目;项目号:[2015]14号 |
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| 摘 要： | 建立从高良姜中制备山柰素对照品的方法,结合吸附树脂和制备型高效液相色谱对高良姜乙醇提取物进行分离纯化,通过IR、MS和NMR进行结构鉴定,分析型HPLC面积归一化法进行纯度检查和含量测定,得山柰素对照品纯度符合国家药典要求,质量分数大于99.8%,建立的制备方法简单,对照品纯度高,可作为山柰素药效物质基础研究的标准对照品。
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| 关 键 词： | 山柰素 高良姜 对照品 制备方法 |
Study on Preparation of Kaempferide Reference Substance From Alpinia officinarum Hance |
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| HOU Hong-rui,CHEN Ling,WANG Chun-xiao,SUN Guo-yong,ZHANG Xiao-feng. Study on Preparation of Kaempferide Reference Substance From Alpinia officinarum Hance[J]. Contemporary Chemical Industry, 2017, 46(2) |
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| Authors: | HOU Hong-rui CHEN Ling WANG Chun-xiao SUN Guo-yong ZHANG Xiao-feng |
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| Abstract: | A preparation method of kaempferide reference substance from Alpinia officinarum Hance was established;the extract from Alpinia officinarum Hance was isolated and purified by adsorption resin and preparative HPLC.The structure of kaempferide reference substance was identified by IR,MS and NMR.The purity of the product was quantitated by analytical HPLC area normalization method,the mass fraction was above 99.8％.This method is effective for preparation of kaempferide with high purity.It can be used to prepare the reference substances for the quantitative analysis of Chinese materia medica. |
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| Keywords: | Kaempferide Alpinia-officinarum Hance Reference substance Preparation |
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