| 茶多酚肉碱复方制剂降血脂的实验研究 |
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| 引用本文： | 倪辉,刘小杰. 茶多酚肉碱复方制剂降血脂的实验研究[J]. 食品研究与开发, 2011, 32(8): 140-142 |
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| 作者姓名： | 倪辉 刘小杰 |
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| 作者单位： | 1. 集美大学生物工程学院,福建厦门,361021
2. 浙江工业大学生物与环境工程学院,浙江杭州,310014 |
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| 基金项目： | 集美大学科研创新团队基金(2010A006) |
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| 摘 要： | 探讨茶多酚肉碱复方制剂对高脂血症模型大鼠血脂水平的影响。采用高脂饲料喂养SD大鼠建立预防性高脂血症模型,将实验大鼠分成正常对照组、模型对照组、低剂量组、中剂量组和高剂量组。连续灌胃给药45 d,观察茶多酚肉碱复方制剂对高脂血症大鼠血清甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)的影响。结果表明,与正常对照组比较,高脂饲料连续喂养45 d后,模型对照组大鼠血清TG和TC显著升高(P<0.01);与模型对照组比较,给药45 d后,1)低剂量组大鼠血清TG未见显著性降低(P>0.05),中剂量组和高剂量组血清TG极显著地降低(P<0.01);2)低剂量组大鼠血清TC显著降低(P<0.05),中高剂量组大鼠血清TC极显著降低(P<0.01);3)各剂量组大鼠血清HDL-C无显著性差异。茶多酚肉碱复方制剂具有辅助降血脂的作用。
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| 关 键 词： | 茶多酚 左旋肉碱 总黄酮 甘油三酯 总胆固醇 |
Experimental Study on Blood Lipid-lowering of Tea Polyphenois and Carnitine Preparation |
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| NI Hui,LIU Xiao-jie. Experimental Study on Blood Lipid-lowering of Tea Polyphenois and Carnitine Preparation[J]. Food Research and Developent, 2011, 32(8): 140-142 |
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| Authors: | NI Hui LIU Xiao-jie |
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| Affiliation: | NI Hui1,LIU Xiao-jie2(1.College of biotechnology,Jimei University,Xiamen 361021,Fujian,China,2.College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou 310014,Zhejiang,China) |
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| Abstract: | To investigate the effect of tea polyphenols and carnitine preparation on plasma lipid levels of hyperlipidemic rats.SD rats were fed high fat diet and established as preventive hyperlipidemia model,the experimental rats were divided into normal control group,model group,low dose group,middle dose group and high dose group.After 45 days continuous oral administration,the effect of tea polyphenols and carnitine preparation on serum triglyceride(TG),total cholesterol(TC) and high density lipoprotein cholester... |
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| Keywords: | tea polyphenols L-Carnitine total flavonoid triglyceride total cholesterol |
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