The determination of opiates by latex agglutination

A method based on latex agglutination test has been developed for detection of opiates in human urine. Specific reagents were synthesized and conditions of interaction of conjugated latex antigens with specific antibodies to morphine in the presence of an inhibitor were examined. Sensitivity of the method was 100 ng/ml. The developed latex agglutination test for detection of opiates may be used in combination with enzyme immunoassay in practical forensic medicine and narcology.