食源性抗炎活性肽对肠道炎症的作用研究进展

炎症是机体对感染、伤害或化学刺激引起的防御反应。慢性炎症会反复破坏细胞和组织，从而诱发包括肠道炎症等多种疾病。食源性生物活性肽具有来源广泛、吸收速度快、安全性高等优点，近年来研究发现食源性生物活性肽具有一定的抗炎活性并对维持肠道健康起着积极作用，在炎症性肠病的防治中具有广阔的应用前景。本文就肠道炎症治疗现状，对目前国内外食源性抗炎活性肽的来源、制备、分离纯化、鉴定、抗炎活性评价及作用机制予以综述，并探讨了食源性抗炎活性肽的应用现状，对此研究领域的发展趋势予以展望，旨在为肠道健康功能性食品的研究及开发提供参考。

Progress in the Study of the Effect of Food-Derived Anti-inflammatory Peptides on Intestinal Inflammation

Inflammation is the body’s defense response to infection, injury or chemical stimulation. Chronic inflammation can repeatedly destroy cells and tissues, leading to a variety of human diseases including intestinal inflammation. Food-derived bioactive peptides can be obtained from a wide varieties of sources and be rapidly absorbed, and are safe. In recent years, it has been found that food-derived bioactive peptides have anti-inflammatory activity and play an active role in maintaining intestinal health, and are thus promising for the prevention and treatment of inflammatory bowel disease. Beginning with a summary of the current status of intestinal inflammation treatments, this paper reviews the sources, preparation, purification, identification, anti-inflammatory, activity evaluation and action mechanism of anti-inflammatory peptides, and discusses the current status of their application and future trends in this field of research. We expect that this review will provide a reference for the research and development of functional foods for intestinal health.