| 2'-岩藻糖基乳糖预防婴幼儿坏死性小肠结肠炎及感染性腹泻的研究进展 |
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| 引用本文： | 陆梦兰,陈财龙,徐加英,石羽杰,苏红文,刘彪,秦立强.2'-岩藻糖基乳糖预防婴幼儿坏死性小肠结肠炎及感染性腹泻的研究进展[J].食品工业科技,2021,42(23):408-412. |
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| 作者姓名： | 陆梦兰 陈财龙 徐加英 石羽杰 苏红文 刘彪 秦立强 |
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| 作者单位： | 1.苏州大学公共卫生学院，江苏苏州 2151232.苏州大学放射医学与防护学院，江苏苏州 2151233.内蒙古伊利实业集团股份有限公司金山分公司，内蒙古呼和浩特 010110 |
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| 摘 要： | 婴幼儿尤其是新生儿消化和免疫功能不全、肠道发育不成熟，导致肠道耐受性差和细菌定植困难，并对坏死性小肠结肠炎和感染性腹泻高度敏感。母乳喂养对婴幼儿肠道健康的益处有赖于母乳中特殊的低聚糖，2'-岩藻糖基乳糖是母乳中含量较高的低聚糖。本文综述了2'-岩藻糖基乳糖的安全性，对肠道菌群及免疫系统的调节，以及对预防婴幼儿坏死性小肠结肠炎和感染性腹泻作用的研究进展。
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| 关 键 词： | 2'-岩藻糖基乳糖 母乳低聚糖 腹泻 坏死性小肠结肠炎 婴幼儿配方奶粉 |
| 收稿时间： | 2020-10-29 |
Protective Effect of 2'-Fucosyllactose on Necrotizing Enterocolitis and Infectious Diarrhea in Infants |
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| LU Menglan,CHEN Cailong,XU Jiaying,SHI Yujie,SU Hongwen,LIU Biao,QIN Liqiang.Protective Effect of 2'-Fucosyllactose on Necrotizing Enterocolitis and Infectious Diarrhea in Infants[J].Science and Technology of Food Industry,2021,42(23):408-412. |
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| Authors: | LU Menglan CHEN Cailong XU Jiaying SHI Yujie SU Hongwen LIU Biao QIN Liqiang |
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| Affiliation: | 1.School of Public Health, Soochow University, Suzhou 215123, China2.School of Radiation Medicine and Protection, Soochow University, Suzhou 215123, China3.Jinshan Branch Company, Inner Mongolia Yili Industrial Group Co., Ltd., Hohhot 010110, China |
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| Abstract: | Infants, especially newborns, have poor digestion and immune function and immature intestinal development, leading to poor intestinal tolerance and difficulty in bacterial colonization, and highly sensitivity to necrotizing enterocolitis and infectious diarrhea. The benefits of breast feeding for infant intestinal health depend on a special oligosaccharide, and 2'-fucosyllactose (2'-FL) is the higher content of oligosaccharides. This paper describes the safety of 2'-FL, regulation of intestinal flora and immune system, and its protective effect on necrotizing enterocolitis and infectious diarrhea in infants. |
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