| 牛乳来源外泌体的生物学功能研究进展 |
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| 引用本文： | 周志立,黄桂东,钟先锋,张宇博. 牛乳来源外泌体的生物学功能研究进展[J]. 食品工业科技, 2021, 42(11): 372-381. DOI: 10.13386/j.issn1002-0306.2020060381 |
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| 作者姓名： | 周志立 黄桂东 钟先锋 张宇博 |
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| 作者单位： | 1.佛山科学技术学院食品科学与工程学院，广东佛山 5282312.广东省传统发酵食品工程技术研究中心，广东佛山 5282313.广东省食品流通安全控制工程技术研究中心，广东佛山 5282314.佛山市酿造工程技术研究中心，广东佛山 5282315.佛山农业生物制造工程技术研究中心，广东佛山 528231 |
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| 摘 要： | 外泌体是由细胞分泌到细胞外的一种胞外囊泡,装载了许多有着特定功能的活性物质,包括核酸、脂质和蛋白质等.绝大多数的活细胞都能够分泌外泌体并且将其所携带的内容物传递至靶细胞发挥特定的作用.而牛乳所分泌的外泌体已被证实对人体先天免疫、肠道发育等方面具有积极功效.同时,牛乳来源的外泌体也被证实会对罹患肥胖、II型糖尿病等慢性疾...
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| 关 键 词： | 外泌体 牛乳 组成 风险 功能特性 |
| 收稿时间： | 2020-07-02 |
Research Progress on Biological Functions of Exosomes Derived from Bovine Milk |
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| ZHOU Zhili,HUANG Guidong,ZHONG Xianfeng,ZHANG Yubo. Research Progress on Biological Functions of Exosomes Derived from Bovine Milk[J]. Science and Technology of Food Industry, 2021, 42(11): 372-381. DOI: 10.13386/j.issn1002-0306.2020060381 |
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| Authors: | ZHOU Zhili HUANG Guidong ZHONG Xianfeng ZHANG Yubo |
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| Affiliation: | 1.Foshan University Department of Food Science, Foshan 528231, China,2.Guangdong Engineering Research Center for Traditional Fermentational Food, Foshan 528231, China,3.Guangdong Engineering Research Center for Safety Control of Food Circulation, Foshan 528231, China,4.Foshan Engineering Research Center for Brewing Technology, Foshan 528231, China,5.Foshan Engineering Research Center for Agricultural Biological Manufacturing, Foshan 528231, China |
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| Abstract: | Exosomes, as a kind of extracellular vesicles, are secreted by cells into the extracellular. It is loaded by many active substances with specific functions, including nucleic acids, lipids, proteins, etc. The vast majority of living cells can secrete exosomes and transfer the components to the target cells to play a specific role. The exosomes secreted by cow’s milk have been proved to have good effects on human innate immunity and intestinal development. At the same time, exosomes derived from cow’s milk have also been proved to bring potential risks to the development of chronic diseases such as obesity and type 2 diabetes. This article reviews the composition and formation of exosomes, as well as the beneficial functional characteristics and some potential risks of milk exosomes to human body. It is expected to provide reference for research on milk exosomes. |
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