婴幼儿奶粉中阪崎克罗诺杆菌隐性污染状况分析及针对性检测技术研究进展

婴幼儿奶粉中存在的阪崎克罗诺杆菌对婴幼儿危害性极强，卫生标准中对该微生物有严格限制，但检出现象仍然时有发生。存在许多因素导致阪崎克罗诺杆菌在婴幼儿奶粉生产线中的潜伏，本文阐述了其在生产空间中的暴露特征，重点论述逆境胁迫下该菌耐受表型和活的非可培养表型形成的隐性污染对监测和清除污染残留的不利影响。讨论了各类检测技术的优缺点，强调检测灵敏度、回收率和区分活的非可培养状态菌对于控制隐性污染的重要性。以期为阪崎克罗诺杆菌的监测和防控提供新思路，为保障婴幼儿奶粉生产安全提供参考和建议。

Cronobacter sakazakii in Powdered Infant Formula: Analysis of Hidden Contamination Status and Detection Technologies

Cronobacter sakazakii in powdered infant formula is extremely harmful to infants. While hygienic standards for infant formula have imposed a strict limit for this microorganism, Cronobacter sakazakii-tainted baby formula incidents continue to occur. There are many factors that contribute to the occurrence of Cronobacter sakazakii in the production line of powdered infant formula. This article describes the characteristics of spatial exposure of powdered infant formula to Cronobacter sakazakii during the production process, focusing on the adverse effects on the monitoring and removal of Cronobacter sakazakii residues caused by hidden contamination associated with the stress-tolerant phenotype and viable but non-culturable (VBNC) phenotype in Cronobacter sakazakii. The advantages and disadvantages of the existing detection technologies for Cronobacter sakazakii are discussed, highlighting the importance of detection sensitivity, recovery and identification of VBNC cells in the control of hidden contamination. It is hoped that this review will provide new ideas for the monitoring and prevention of Cronobacter sakazakii during infant formula production.