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食物血糖应答测试方法研究进展
引用本文:丁方莉,柳嘉,林静,高铭,王晴,苑鹏,韩晓峰,陈伟,段盛林.食物血糖应答测试方法研究进展[J].食品工业科技,2021,42(1):355-362.
作者姓名:丁方莉  柳嘉  林静  高铭  王晴  苑鹏  韩晓峰  陈伟  段盛林
作者单位:1. 中国食品发酵工业研究院有限公司, 北京 100015;2. 功能主食创制与慢病营养干预北京市重点实验室, 北京 100015;3. 中国医学科学院北京协和医院临床营养科, 北京 100730
基金项目:"十三五"国家重点研发计划重点专项(2016YFD0401303);沙棘资源高值化加工技术及功能性食品开发与应用(19223002D)。
摘    要:血糖应答是指食物对血糖水平变化的影响,能够反映食物中的碳水化合物在体内的消化代谢状态,因此食物血糖应答的测定对于糖尿病患者的膳食指导以及低血糖生成指数产品的研发过程等均有着非常重要的意义。目前最权威的测试食物血糖应答的方法是人体测试。此外,动物试验和体外消化模型由于具有简便易行、成本较低以及可大量测试食物原料等优势,也逐渐成为研究的热点。本文主要对血糖应答测试的方法包括人体测试、动物试验以及体外消化模型的研究现状进行综述,以期为后续的相关研究提供一定的指导和帮助。

关 键 词:食物血糖应答    血糖指数    人体测试    动物试验    体外消化模型
收稿时间:2020-03-13

Review on Test Methods of Food Glycemic Responses
DING Fang-li,LIU Jia,LIN Jing,GAO Ming,WANG Qing,YUAN Peng,HAN Xiao-feng,CHEN Wei,DUAN Sheng-lin.Review on Test Methods of Food Glycemic Responses[J].Science and Technology of Food Industry,2021,42(1):355-362.
Authors:DING Fang-li  LIU Jia  LIN Jing  GAO Ming  WANG Qing  YUAN Peng  HAN Xiao-feng  CHEN Wei  DUAN Sheng-lin
Affiliation:1. China National Research Institute of Food and Fermentation Industries Co., Ltd., Beijing 100015, China;2. Beijing Key Laboratory of the Innovative Development of Functional Staple and the Nutritional Intervention for Chronic Disease, Beijing 100015, China;3. Department of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
Abstract:Glycemic response(GR)refers to the effect of food on blood glucose fluctuation,which can reflect the digestion and metabolism of carbohydrate in the body. The determination of GR is very important for the diet guidance for diabetic patients,and the development of low glycemic index products. At present,the most authoritative method to test GR is human body test. In addition,animal test and in vitro evaluation methods have also become research focuses due to their advantages of low cost,easy operation and high throughput. This paper mainly reviews the research status of different methods on GR test including human test,animal test and in vitro digestion model,in order to provide guidance and help for the follow-up research.
Keywords:
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