| 高强度力学性能丝素/羟基磷灰石多孔支架材料的初步制备 |
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| 引用本文： | 徐水,张胡静,张海萍,杨明英,朱良均. 高强度力学性能丝素/羟基磷灰石多孔支架材料的初步制备[J]. 高分子材料科学与工程, 2011, 0(10): 150-153 |
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| 作者姓名： | 徐水 张胡静 张海萍 杨明英 朱良均 |
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| 作者单位： | 西南大学生物技术学院;浙江大学动物科学学院应用生物资源研究所; |
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| 摘 要： | 以丝素和羟基磷灰石为基材,磷酸盐缓冲液为溶剂,戊二醛为交联剂制备丝素/羟基磷灰石支架材料,对丝素生物材料在骨材料中的开发应用有积极意义。研究表明,丝素/羟基磷灰石复合材料具有结晶结构和β构象。当丝素与羟基磷灰石的比例为6/4时,支架材料的弹性模量和压缩强度达到最大,分别为48.087 MPa和1.427 MPa,孔隙率...
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| 关 键 词： | 丝素 羟基磷灰石 支架 结构 力学性能 |
A Method to Construct a High Mechanical Property's Silk Fibroin/Hydroxyapatite Scaffold |
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| Shui Xu,Hujing Zhang,Haiping Zhang,Mingying Yang,Liangjun Zhu. A Method to Construct a High Mechanical Property's Silk Fibroin/Hydroxyapatite Scaffold[J]. Polymer Materials Science & Engineering, 2011, 0(10): 150-153 |
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| Authors: | Shui Xu Hujing Zhang Haiping Zhang Mingying Yang Liangjun Zhu |
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| Affiliation: | Shui Xu1,Hujing Zhang1,Haiping Zhang2,Mingying Yang2,Liangjun Zhu2(1.Institute of Technology,Southwest University,Chongqing 400715,China,2.Institute ofApplied Bioresources,College of Animal Science,Zhejiang University,Hangzhou 310029,China) |
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| Abstract: | The fibroin/hydroxyapatite scaffold was successfully prepared by dissolving fibroin and hydroxyapatite in the phosphate buffer,cross-linked by glutaral dehyde in moderate condition,which possesses both crystalline structure and β parallel.This study offered a potential benefits for the exploration and utilization of fibroin in the artificial bone.The result shows that the maximum and compressive strength of this scaffold can attain about 48.087MPa and 1.44MPa,respectively,when the ration of fibroin/hydroxyapatite is 6/4.The porosity is 70%.The pore size range is from 50 um to 200 um.All the results suggest this new method highly promotes the scaffold′s mechanical,approaching the cancellous bone of human. |
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| Keywords: | fibroin hydroxyapatite scaffold structure mechanical properties |
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