Colony formation efficiency in agar cultures of the bone marrow and spleen from intact mice in diffusion chambers implanted in the abdominal cavity of mice with Lewis pulmonary carcinoma

In C57Bl/6 mice with different stages of Lewis lung carcinoma growth used as recipients of diffusion chambers, after subcutaneous transplantation of tumour cells there was an increased output of colonies in the bone marrow and spleen cell cultures (CFU-DC) as compared to the control, The cocultivation of normal (bone marrow and spleen) and tumour cells has no influence on the effectiveness of their cloning.