3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches |
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| Authors: | Boriss Strumfs Romans Uljanovs Kirils Velikijs Peteris Trapencieris Ilze Strumfa |
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| Affiliation: | 1.Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006 Riga, Latvia; (B.S.); (P.T.);2.Department of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia; (R.U.); (K.V.) |
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| Abstract: | Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination. |
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| Keywords: | aziridines aziridination imines carbenes nitrenes |
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