海南省婴幼儿配方奶粉中反式脂肪酸的 风险性评估

目的对婴幼儿经食用婴幼儿配方奶粉途径摄入反式脂肪酸的风险进行评价。方法采用气相色谱法检测婴幼儿配方奶粉中反式脂肪酸的含量,运用基于蒙特卡罗模拟的Stata 12软件,以风险商表征婴幼儿经食用婴幼儿配方奶粉途径的反式脂肪酸膳食风险。结果反式脂肪酸日均暴露量的平均值为0.0001281 kg/d;海南普通婴幼儿通过食用婴幼儿配方奶粉途径摄入反式脂肪酸的风险商平均值和各百分位数风险商均小于1,且婴幼儿配方奶粉中反式脂肪酸含量的敏感性最强,占99.1%,拉平时间为负值,表明它对反式脂肪酸日均暴露量起负面的影响。结论海南普通婴幼儿仅通过食用婴幼儿配方奶粉途径的反式脂肪酸膳食暴露尚不存在健康风险,但是仍需加强对婴幼儿配方奶粉中反式脂肪酸的控制和监测,从而进一步降低海南乃至全国普通婴幼儿食用婴幼儿配方奶粉途径的反式脂肪酸膳食风险水平。

Exposure assessment of the content of trans fatty acids of formula milk powder for infant and young children in Hainan Province

Objective To assess the risk of infant and young children intake of trans-fatty acids (TFA) by consumption of formula milk powder. Methods The content of trans fatty acids of formula milk powder for infant and young children was determined by gas chromatographic method. Hazard quotient was employed to characterize the dietary risk of trans-fatty acids via eating formula milk powder for infant and young children with the application of Stata 12 software basing on Monte Carlo simulation. Results The results showed the average daily exposure dose of intake of TFA in Hainan province was 0.0001281 kg/d. The average and each percentile of the hazard quotient of general population through consuming formula milk powder for infant and young children were all less than 1. Moreover, the sensitivity of the content of TFA of formula milk powder was strongest, accounting for 99.1%. The even time was negative, it was indicated that it had negative effects on daily exposure of TFA. Conclusion Therefore, to the general infant and young children, the dietary exposure of TFA only by formula milk powder was unlikely to bring about severe health risk. But the control and monitoring of TFA in formula milk powder should be strengthened to further reduce the dietary TFA risk level of the infant and young children.