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Osseointegration of sputtered SiC-added hydroxyapatite for orthopaedic applications
Affiliation:1. Department of Theoretical and Experimental Physics, National Research Tomsk Polytechnic University, Lenin Avenue, 30, 634050 Tomsk, Russia;2. Technological Institute for Superhard and Novel Carbon Materials, Central Street 7а, 142190 Troitsk, Russia;3. Inorganic Chemistry and Center for Nanointegration Duisburg-Essen (CeNIDE), University of Duisburg-Essen, 45117 Essen, Germany;4. Technical Physics and Center for Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, 47057 Duisburg, Germany;5. Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Nobel Street 12, 70569 Stuttgart, Germany;1. WPI Advanced Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan;2. National Engineering Research Center of Near-net-shape Forming for Metallic Materials, School of Mechanical and Automotive Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China;3. Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China;4. Erich Schmid Institute of Materials Science, Austrian Academy of Sciences, Leoben 8700, Austria;5. National University of Science and Technology “MISiS”, Moscow 119049, Russia;6. Institute of Engineering Innovation, The University of Tokyo, Tokyo 113-8656, Japan
Abstract:Over the last few years, a trend in medical applications is to find solutions for metallic implants using coatings that can improve bioactivity and osseointegration. The goal of this study was to obtain and investigate sputtered hydroxyapatite coatings enriched with SiC to enhance the bioactivity and osseointegration of Ti alloys used in orthopaedic applications. The films were characterized in terms of phase composition, roughness, corrosion resistance in a synthetic body fluid (SBF) and in vitro biocompatibility with MG 63 osteoblast-like cells. All of the investigations were conducted using XRD, AFM, cell viability assays and proliferation tests. The results revealed that the addition of SiC had a positive influence on the properties of the sputtered hydroxyapatite. The addition of SiC led to an improvement in coating adhesion and corrosion resistance in an SBF solution over the HAP coating. All of the coatings presented cell viability values over 90%, revealing their suitability for medical applications.
Keywords:B: Porosity  C: Corrosion  D: Apatite  E: Biomedical applications
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