| 氯霉素及其主要降解产物滴眼液的家兔眼刺激试验 |
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| 引用本文： | 袁素华,凌沛学.氯霉素及其主要降解产物滴眼液的家兔眼刺激试验[J].食品与药品,2007,9(2):25-26. |
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| 作者姓名： | 袁素华 凌沛学 |
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| 作者单位： | 山东大学药学院,山东,济南,250012;山东博士伦福瑞达制药有限公司,山东,济南,250014 |
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| 摘 要： | 目的考察氯霉素滴眼液及其主要降解产物滴眼液对兔眼的刺激作用。方法氯霉素滴眼液及其主要降解产物4种滴眼液滴眼,每日6次,每次2滴,连续14d。结果和结论4种滴眼液对兔眼均无明显刺激作用。
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| 关 键 词： | 氯霉素滴眼液 氯霉素二醇物 对硝基苯甲醛 刺激试验 |
| 文章编号： | 1672-979X(2007)02-0025-02 |
| 修稿时间： | 2006年11月1日 |
Irritant Effect of Chloramphenicol Eye Drops and Its Degradation Products on Rabbit Eyes |
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| YUAN Su-hua,LING Pei-xue.Irritant Effect of Chloramphenicol Eye Drops and Its Degradation Products on Rabbit Eyes[J].Food and Drug,2007,9(2):25-26. |
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| Authors: | YUAN Su-hua LING Pei-xue |
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| Abstract: | Objective To test the irritant effect of chloramphenicol eye drops and its degradation products on rabbit eyes.Methods Four kinds of related eye drops containing chloramphenicol or its degradation products were used two drops per time and six times per day for two weeks.Results and Conclusion The four kinds of eye drops have no marked irritant action on the tested rabbit eyes. |
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| Keywords: | chloramphenicol eye drops glycols in chloramphenicol p-nitrobenzaldehyde irritant test |
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