Molecular and Functional Characterization of BDNF-Overexpressing Human Retinal Pigment Epithelial Cells Established by Sleeping Beauty Transposon-Mediated Gene Transfer |
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| Authors: | Larissa Mattern,Katrin Otten,Csaba Miskey,Matthias Fuest,Zsuzsanna Izsvá k,Zoltá n Ivics,Peter Walter,Gabriele Thumann,Sandra Johnen |
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| Affiliation: | 1.Department of Ophthalmology, University Hospital RWTH Aachen, 52074 Aachen, Germany;2.Division of Medical Biotechnology, Paul-Ehrlich-Institute, 63225 Langen, Germany;3.Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany;4.Department of Ophthalmology, University Hospitals of Geneva, 1205 Geneva, Switzerland;5.Experimental Ophthalmology, University of Geneva, 1205 Geneva, Switzerland |
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| Abstract: | |
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| Keywords: | RPE cells BDNF Sleeping Beauty transposon system non-viral transfection cell-based additive gene therapy neurodegenerative retinal diseases AMD |
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