| 介孔生物活性玻璃/脱钙骨复合支架的制备及性能研究 |
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| 引用本文： | 薛士壮,朱海霖,陈建勇,冯新星,常江. 介孔生物活性玻璃/脱钙骨复合支架的制备及性能研究[J]. 无机材料学报, 2011, 26(10): 1068-1072. DOI: 10.3724/SP.J.1077.2011.01068 |
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| 作者姓名： | 薛士壮 朱海霖 陈建勇 冯新星 常江 |
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| 作者单位： | (1. 浙江理工大学 先进纺织材料与制备技术教育部重点实验室, 材料与纺织学院, 杭州 310018; 2. 中国科学院 上海硅酸盐研究所 高性能陶瓷和超微结构国家重点实验室, 上海 200050) |
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| 基金项目： | 国家自然科学基金(50973096,50903073,31070867); 浙江省科技厅公益项目(2010C31038)~~ |
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| 摘 要： | 将介孔生物活性玻璃(MBG)与脱钙骨(DB)复合, 利用浸渍法制备出MBG/DB复合支架材料. 采用红外光谱(FTIR), 扫描电镜(SEM), X射线衍射(XRD), 电子万能材料试验机等方法对牛松质骨(CB)、DB、MBG/DB复合支架进行表征. 结果表明, CB经浸酸处理后制备的DB, 孔径大小在200~600μm范围内, 孔隙率约为71%, 抗压性能比CB明显降低(1.10±0.31)MPa, 而采用浸渍法制备的复合支架, 孔隙率降为40%左右, 而压缩强度明显提高(8.49± 2.14)MPa. 体外生物活性测试表明: 复合支架具有良好的生物活性.
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| 关 键 词： | 介孔生物活性玻璃 脱钙骨 复合支架 生物活性 |
| 收稿时间： | 2010-11-23 |
| 修稿时间： | 2011-01-12 |
Preparation and Properties of Mesoporous Bioactive Glass/Demineralized Bone Composite Scaffolds |
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| XUE Shi-Zhuang,ZHU Hai-Lin,CHEN Jian-Yong,FENG Xin-Xing,,CHANG Jiang. Preparation and Properties of Mesoporous Bioactive Glass/Demineralized Bone Composite Scaffolds[J]. Journal of Inorganic Materials, 2011, 26(10): 1068-1072. DOI: 10.3724/SP.J.1077.2011.01068 |
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| Authors: | XUE Shi-Zhuang ZHU Hai-Lin CHEN Jian-Yong FENG Xin-Xing CHANG Jiang |
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| Affiliation: | (1. Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles; Zhejiang Sci-Tech University, Hangzhou 310018, China; 2. State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China) |
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| Abstract: | The composite scaffolds (MBG/DB) were prepared successfully through immersing the mesoporous bioactive glass powders into the demineralized bones. The bovine cancellous bone, demineralized bone, composite scaffold were investigated and characterized by FTIR, SEM, XRD and universal electromechanical testing machine. The results show that the compressive strength of the demineralized bones is about (1.10±0.31)MPa, the porosity is about 71% and the pore size is in the range from 200 to 600μm. However, the porosity and the compressive strength of the composite scaffolds are decreased to 40% and increase markedly to (8.49±2.14)MPa, respectively. Meanwhile, the composite scaffolds show good bioactivity in vitro. |
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| Keywords: | mesoporous bioactive glass demineralized bone composite scaffold bioactivity |
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