Synthesis and characterization of pH- and temperature-sensitive hydrogel of N-isopropylacrylamide/cyclodextrin based copolymer |
| |
Authors: | Yu-Yang LiuXiao-Dong Fan |
| |
Affiliation: | Department of Chemical Engineering, Northwestern Polytechnic University, Xi'an 710072, People's Republic of China |
| |
Abstract: | A reactive β-Cyclodextrin (β-CD) based monomer carrying vinyl carboxylic acid functional groups was synthesized via reaction of β-CD with maleic anhydride (MAH) in N,N-dimethylformamide (DMF) at 80 °C. By copolymerization of the monomer with N-isopropylacrylamide (NIPA), a novel hydrogel, poly(NIPA-co-MAH-β-CD) with pH and temperature sensitivities plus molecular inclusion function, was obtained using free radical polymerization in aqueous solution. The hydrogel's composition was determined by element analysis and infrared spectroscopy. Equilibrium swelling ratio (ESR) of hydrogels was tested under different environment of pH, temperature and ionic strength. The results indicated that ESR of hydrogels presents marked variations following the change of experimental conditions used. |
| |
Keywords: | β-Cyclodextrin N-Isopropylacrylamide pH- and temperature-sensitive hydrogel |
本文献已被 ScienceDirect 等数据库收录! |
|