聚乳酸合成方法研究进展

聚乳酸是一类具有优良生物相容性和可生物降解的高分子材料,被广泛应用于医用领域,受到越来越多的关注。聚乳酸的合成主要有两种方法:丙交酯的开环聚合和乳酸直接缩聚。本文综述了近年来聚乳酸合成研究的最新进展,介绍了聚乳酸聚合的两种高效方法——反应挤出法和直接—固相聚合法,并展望了聚乳酸合成研究的前景。

Progress in study of synthesis of polylactide

Poly(lactic acid) (poly lactide,PLA)isa biocompatible and bioresorbable polymer,thus it is widely used in the medical area,and is paid much attention to.There are two main methods to synthesis PLA,ring- open- ing polymerization of lactide and condensation polymerization of lactic acid.In the paper,the process of the new re- search of the synthesis PLA was reviewed.Beside,the PLA synthesis methods of reactive extrusion and direct melting polycondensation were introduced,which are two high efficiency methods.Finally,the foreground of PLA synthesis was prospected.