| 光动力结合环磷酰胺对小鼠移植瘤影响的实验研究 |
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| 引用本文： | 易南,王冰水,李玲,王斌. 光动力结合环磷酰胺对小鼠移植瘤影响的实验研究[J]. 激光杂志, 2002, 23(1): 81-83 |
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| 作者姓名： | 易南 王冰水 李玲 王斌 |
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| 作者单位： | 第四军医大学西京医院康复与理疗科 西安710032(易南，王冰水，李玲)，第四军医大学西京医院康复与理疗科 西安710032(王斌) |
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| 摘 要： | 目的 :观察PDT结合环磷酰胺对小鼠移植肿瘤的杀伤效应。方法 :应用光敏剂加氩离子激光照射结合应用环磷酰胺对小鼠移植肿瘤进行治疗。结果 :激光光动力结合环磷酰胺治疗对小鼠移植瘤的杀伤作用较单独应用激光光动力或单独应用环磷酰胺的杀伤作用更明显 (P <0 0 1)。结论 :光动力结合化疗药物可作为治疗肿瘤的一种方法
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| 关 键 词： | 环磷酰胺 小鼠 移植瘤 光动力 |
| 修稿时间： | 2001-08-13 |
Experimental study on transplanted tumor of mice treated by PDT combined with cyclophosphamide |
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| Yi Nan Wang Bingshui Li Ling Wang Bin. Experimental study on transplanted tumor of mice treated by PDT combined with cyclophosphamide[J]. Laser Journal, 2002, 23(1): 81-83 |
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| Authors: | Yi Nan Wang Bingshui Li Ling Wang Bin |
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| Abstract: | Objective:To investigate the effect on transplanted tumor of mice treated by PDT(Photodynamic Therapy,PDT)combined with cylophosphamide.Methods:Photosensitizer was given to the mice before the tumor was irradiated by the laser.Simultaneously cyclophosphamide was given to the mice by the dosage of 5mg/kg continuous for 3 days.Results:Comparing to cyclophosphamide group or PDT group,there was a better effect in PDT combined with cyclophosphamide group.Conclusion:PDT combines with chemotherapy can be a method in treating tumor. |
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| Keywords: | PDT cyclophosphamide mouse transplanted tumor |
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