高速128通道小动物多光谱光声断层成像系统

为了实现小动物光声断层信号的高速采集和实时高质量图像的重建，采用了覆盖角度为270°的128阵元弧形聚焦超声换能器、4个32通道的NI公司数据采集模块和可调谐脉冲激光器以及正则化优化的基于模型的光声断层重建算法。结果表明，系统的空间分辨率可以达到180μm；此系统可以在1ms内完成光声断层数据的采集，在40s以内获得高质量的重建图像。该系统可以用于开展小动物在体的多光谱光声断层成像实验研究。

High-speed and 128-channel multi-spectral photoacoustictomography system for small animal

In order to achieve high-speed acquisition and real-time high-quality image reconstruction of photoacoustic tomography signals for small animal, a 128 element arc-shaped focused ultrasound transducer with 270° coverage angle, four 32 channel NI data acquisition modules, a tunable pulsed laser and model-based photoacoustic tomography reconstruction algorithm with regularized optimization were used.The spatial resolution of the system can be up to 180μm.The in vitro and in vivo imaging experiments show that the system can complete photoacoustic tomography data acquisition within 1ms, and obtain high quality reconstructed images within 40s.The system can be used to carry out in vivo multi-spectral photoacoustic tomography of small animals.