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Determination of the synthetic origin of methamphetamine samples by 2H NMR spectroscopy
Authors:Armellin Silvia  Brenna Elisabetta  Frigoli Samuele  Fronza Giovanni  Fuganti Claudio  Mussida Daniele
Affiliation:Dipartimento di Chimica, Materiali, Ingegneria Chimica, Politecnico di Milano, and Istituto CNR per la Chimica del Riconoscimento Molecolare, Via Mancinelli 7, I-20131 Milano, Italy.
Abstract:Samples of methamphetamine, prepared according to the most common synthetic pathways, were submitted to natural-abundance 2H NMR spectroscopy. The deuterium content at the various sites of the molecule was found to depend on its synthetic history. The technique provides a chemical fingerprint of methamphetamine samples and can give hints to trace back the starting materials and the synthetic procedures.
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