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Lipid Nanotechnology
Authors:Samaneh Mashaghi  Tayebeh Jadidi  Gijsje Koenderink  Alireza Mashaghi
Affiliation:1.Zernike Institute for Advanced Materials, Centre for Synthetic Biology, Nijenborgh 4, 9747 AG Groningen, The Netherlands; E-Mail: ;2.Department of Physics, University of Osnabrück, Barbarastraße 7, 49076 Osnabrück, Germany; E-Mail: ;3.FOM Institute AMOLF, Science Park 104, 1098XG Amsterdam, The Netherlands; E-Mail: ;4.Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands
Abstract:Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices and machines derived from engineering, physics, materials science, chemistry and biology. These devices have found applications in biomedical sciences, such as targeted drug delivery, bio-imaging, sensing and diagnosis of pathologies at early stages. In these applications, nano-devices typically interface with the plasma membrane of cells. On the other hand, naturally occurring nanostructures in biology have been a source of inspiration for new nanotechnological designs and hybrid nanostructures made of biological and non-biological, organic and inorganic building blocks. Lipids, with their amphiphilicity, diversity of head and tail chemistry, and antifouling properties that block nonspecific binding to lipid-coated surfaces, provide a powerful toolbox for nanotechnology. This review discusses the progress in the emerging field of lipid nanotechnology.
Keywords:soft nanotechnology  supramolecular chemistry  hybrid materials  synthetic biology  self-assembly  nanoparticle  nanomedicine  nanofluidics  nanoelectronics  lab-on-a-chip
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