Sevoflurane in pediatric ear, nose, and throat procedures |
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| Authors: | EK Motoyama |
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| Affiliation: | Department of Pathology, Washington University School of Medicine, St Louis, MO 63110-1093, USA. |
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| Abstract: | Activation of the Saccharomyces cerevisiae PHO5 gene is accompanied by the disruption of four positioned nucleosomes at the promoter. The chromatin transition requires a DNA-binding protein, Pho4, and its transactivation domain. The mechanism of nucleosome disruption and the contribution of the nucleosomes to PHO5 regulation are reviewed. |
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