新型氨基化磁性纳米粒子的合成

通过嫁接方法在包有二氧化硅的纳米CoFe2O4磁粒表面进行氨基化修饰,制备出一种可用于生物医学领域的新型氨基化纳米磁粒,采用TGA-DTA,IR,VSM和Zeta-potential等测定方法,对氨基化和未氨基化的CoFe2O4纳米粒子进行了表征。元素分析结果显示,有0.98 mmol/g的有机分子固定在纳米粒子表面;红外和热分析数据显示,带氨基的有机分子嫁接到磁粒表面的二氧化硅壳层上;Zeta电位数据也显示,带氨基的有机分子嫁接到纳米磁粒表面;样品的磁性参数显示,氨基化纳米磁粒仍具有好的磁学性能。

Synthesis of a newly aminated magnetic nanoparticles

Synthesis of a kind of newly aminated CoFe2O4 nanoparticles by grafting process for biomedical applications,which were coated primarily with silicon dioxide(SiO2).The aminated SiO2/CoFe2O4(ASCN) and SiO2-coated CoFe2O4(SCN) nanoparticles were investigated by elemental analysis,TGA-DTA,IR,Zeta-potential measurement and VSM.Based on IR and TGA results,it was suggested that the surface of the SiO2-coated CoFe2O4 nanoparticles were grafted with amino compounds.The elemental analysis also showed that 0.98 mmol/g of organic moieties immobilized on the surface of ASCN nanoparticles.Zeta-potential data of ASCN nanoparticles also revealed that amino compounds was bonded onto the surface of SiO2-coated CoFe2O4 nanoparticles by ether linkage.The magnetic parameters showed that ASCN nanoparticles still had good magnetic behavior.