Bile acid pool in wistar rats |
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| Authors: | M. M. Fisher G. Kakis I. M. Yousef |
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| Affiliation: | (1) Departments of Medicine and Pathology, University of Toronto, M5S 1A8 Toronto, Ontario, Canada;(2) Department of Pathology, University of Toronto, M5S 1A8 Toronto, Ontario, Canada |
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| Abstract: | The bile acid pool was found to be ca. 50 μmoles/100 g body wt in male and female rats maintained on standard laboratory chow and ca. 30 μmoles/100 g body wt in those maintained on a standard semisynthetic diet. The distribution of bile acids within the pool was similar in plasma, liver, and intestinal tract, except for a higher concentration of deoxycholic acid in the intestinal tract. Sex differences in bile acid composition were found to be influenced by the dietary regimen of the animals. |
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