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Sample collection guidelines for trace elements in blood and urine. IUPAC Commission of Toxicology
Authors:R Cornelis  B Heinzow  RF Herber  JM Christensen  OM Poulsen  E Sabbioni  DM Templeton  Y Thomassen  M Vahter  O Vesterberg
Affiliation:Laboratory of Analytical Chemistry, University of Gent, Belgium.
Abstract:This paper presents an organized system for element-specific sample collection and handling of human blood (whole blood, serum or plasma, packed cells or erythrocytes) and urine also indicating a proper definition of the subject and sample. Harmonized procedures for collection, preparation, analysis and quality control are suggested. The aim is to assist scientists worldwide to produce comparable data which will be useful on a regional, national and international scale. The guidelines are directed to the elements aluminium, arsenic, cadmium, chromium, cobalt, copper, lead, lithium, manganese, mercury, nickel, selenium and zinc. These include the most important elements measured for their occupational or clinical significance, and serve as examples of principles that will guide development of methods for other elements in the future.
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