Rapid and sensitive detection of enteroviruses in specimens from patients with aseptic meningitis |
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Authors: | S Yerly A Gervaix V Simonet M Caflisch L Perrin W Wunderli |
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Affiliation: | Central Laboratory of Virology, Geneva University Hospital, Switzerland. |
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Abstract: | A 5-h PCR assay (Amplicor enterovirus test) was compared with viral culture for the detection of enteroviruses in cerebrospinal fluid. Of the cerebrospinal fluid specimens collected during a summer outbreak of aseptic meningitis, 34% were positive by viral culture whereas 66% were positive by the Amplicor PCR, suggesting that this technique improves the diagnosis of enteroviral meningitis. |
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