乌司他丁治疗急性胰腺炎的临床疗效评价

目的: 观察乌司他丁(UTI)治疗各型急性胰腺炎(AP)的临床疗效。方法: 将102 例急性胰腺炎患者随机分成2 组,对照组51 例(轻症38 例、重症I 型13 例);治疗组51 例(轻症38 例、重症I 型13 例)。对照组采用综合基础治疗,治疗组在综合基础治疗的基础上加用乌司他丁。按痊愈、显效、有效和无效四级评定疗效。结果: 治疗组轻症有效率为92.1 %,重症I 型为84.6 %;对照组轻症有效率为71.1 %,重症I 型为38.5 %,两组有显著差异性(P<0.05),治疗组对腹痛、血尿淀粉酶、白细胞和TB等的恢复明显优于对照组(P<0.05)。结论: 乌司他丁用于治疗急性水肿型胰腺炎和重症I型均有较好疗效,不良反应较少。

Clinical evaluation of efficacy of ulinastatin in treatment of patients with acute pancreatitis

AIM: To observe the clinical effects of ulinasta-tin (UTI) in treatment of patients with acute pancreatitis (AP).METHODS: 102 patients with acute pancreatitis were randomly divided into two groups.There were 51 cases (38 cases of light type, 13 cases of severe type I) in control group, which were given conventional treatment.There were 51 cases (38 cases of light type, 13 cases of severe type I) in treatment group, which were given conventional treatment and UTI.Clinical results were assessed as cured, significant effective, effective and non-effective.RESULTS: The effective rate was 92.1 %in light type, 84.6 % in severe type I in treatment group, while the effective rate was 71.1 % in light type, and 38.5 %in severe type I in control group (P<0.05).The therapeutic effects in treatment group were better than those of in control group (P<0.05) for releasing abdominal distention, amylase, white blood cells and TB.CONCLUSION: UTI is an effective agents in treating AP (light type and severe type I) with fewer side effects.