超声波辅助活性炭负载杂多酸盐催化合成尼泊金丁酯

以对羟基苯甲酸和正丁醇为原料,活性炭负载Keggin型杂多酸盐(CH_2)_5NH_2]_4SiMo_(12)O_(40)为催化剂,在超声波辐射下合成尼泊金丁酯。考察了催化剂用量、原料配比、超声波辐射功率及辐射时间对尼泊金丁酯收率的影响。结果表明:超声波辐射下活性炭负载Keggin型杂多酸盐(CH_2)_5NH_2]_4SiMo_(12)O_(40)具有良好的催化活性。较佳工艺条件为:对羟基苯甲酸4.14 g(0.03 mo1),酸醇摩尔比1.0:2.0,环己烷40 mL,催化剂7g,450 W超声波辐射20 min。尼泊金丁酯收率达到97%以上。

CATALYTIC SYNTHESIS OF BUTYL PARABEN WITH ACTIVATED CARBON SUPPORTED HETEMPOLY COMPOUND BY ULTRASONIC ASSISTED METHOD

The butyl paraben was synthesized with-p-hydroxy benzoic acid and n-butanol by ultrasonic assisted method,,with activated carbon supported keggin-structured hetempoly compound, (CH_2)_5NH_2]_4SiMo_(12)O_(40),as catalysts.Effects of catalyst dosage,molar ratios of the reactants,ultrasonic wave power and radiation time were investigated.The results showed that the catalytic activity is good under ultrasonic and the optimal conditions were determined as follows:p-hydroxy benzoic 4.14 g(0.03 mol),mole ratio of p-hydroxy benzoic acid to n-butanol 1.0:2.0,cyclohexane 40 mL, catalyst 7 g as well as radiation time 20 min with the ultrasonic wave power of 450 W.Under these conditions,the yield of butyl paraben was up to 97%.