乙苯液相氧化制备苯乙酮催化剂的研究进展

苯乙酮是重要的有机合成中间体，当前主要通过乙苯直接空气氧化法合成苯乙酮的技术路线存在转化率低，副产物多等不足。利用绿色催化剂由乙苯氧化直接合成苯乙酮则具有重大的潜在经济效益、社会效益和环境效益，已成为催化与有机合成等研究领域中极具挑战性的热点课题之一。较为系统地总结了乙苯液相氧化合成苯乙酮的研究工作，首先对其反应机理进行了简述，然后着重综述了用于该反应的催化体系如过渡金属化合物、过渡金属络合物、杂多化合物、分子筛以及其他化合物等。最后，对乙苯氧化合成苯乙酮反应催化体系的研究提供了一些建议和展望。

Advances in development of catalysts for liquid-phase oxidation of ethylbenzene to acetophenone

Acetophenone is an important intermediate in organic synthesis. Currently, acetophenone is produced from direct air oxidation of ethylbenzene process, which cause low conversion rate and more by product. Acetophenone synthesis from the direct catalytic oxidation of ethylbenzene by green catalyst is attractive from the standpoint of its potential economical benefit, social benefit as well as environmental ben- efit. The research works in this field are still regarded as one of the most difficult challenges for both catalysis and organic synthesis. This mini-review systematically summarizes the progress of direct acetophenone synthesis by catalytic oxidation of ethylbenzene, mechanism of the reaction was discussed firstly,and then with emphasis on the explored catalysts such as transition metal compounds, transition metal contact complex, heteropoly complex, molecular sieve and other compounds. Finally, some suggestions are given for future investigation on direct acetophenone synthesis by oxidation of ethylbenzene in the presence of catalysts.