Amygdala atrophy and seizure outcome after temporal lobe epilepsy surgery |
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Authors: | SS Ho D Consalvo F Gilliam E Faught E Bilir R Morawetz RI Kuzniecky |
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Affiliation: | Department of Neurology, UAB Epilepsy Center, University of Alabama at Birmingham, USA. |
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Abstract: | Surgical outcome in hippocampal atrophy (n = 44) and amygdalohippocampal atrophy (n = 14) were compared. Hippocampal atrophy had better seizure-free outcome than amygdalohippocampal atrophy (80% versus 50%, p = 0.043). Severity of hippocampal atrophy correlated with duration of epilepsy in patients with hippocampal atrophy (r = 0.4, p = 0.007), but not in those with amygdalohippocampal atrophy, suggesting that these two groups may have a different pathogenesis. |
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