| 微波辅助1-(对甲氧基苄基)-2-(对甲氧基苯基)苯并咪唑的合成及表征 |
| |
| 引用本文： | 吕维忠,刘波,韦少慧,吴奕光.微波辅助1-(对甲氧基苄基)-2-(对甲氧基苯基)苯并咪唑的合成及表征[J].精细石油化工,2007,24(1):29-31. |
| |
| 作者姓名： | 吕维忠 刘波 韦少慧 吴奕光 |
| |
| 作者单位： | 深圳大学理学院,深圳,518060;深圳大学理学院,深圳,518060;深圳大学理学院,深圳,518060;深圳大学理学院,深圳,518060 |
| |
| 摘 要： | 在微波辐射下,用乙醇作溶剂,以邻苯二胺和对甲氧基苯甲醛为原料合成了1-(对甲氧基苄基)-2-(对甲氧基苯基)苯并咪唑,利用正交法优化了反应条件,较佳条件为:n(对甲氧基苯甲醛):n(邻苯二胺)=2．2:1,微波辐射时间20min,反应温度78℃,产率40%。产物用熔点测试、IR、~1H NMR、~(13)C NMR进行了表征。
|
| 关 键 词： | 微波辐射 苯并咪唑 邻苯二胺 对甲氧基苯甲醛 正交实验 |
| 收稿时间： | 2006-07-18 |
| 修稿时间： | 2006-12-13 |
SYNTHESIS AND CHARACTERIZATION OF 1-(p-METHOXYBENZYL)-2-(p-METHOXYPHENZYL)-BENZIMIDAZOLE UNDER MICROWAVE IRRADIATION |
| |
| Lü Weizhong,Liu Bo,Wei Shaohui,Wu Yiguang.SYNTHESIS AND CHARACTERIZATION OF 1-(p-METHOXYBENZYL)-2-(p-METHOXYPHENZYL)-BENZIMIDAZOLE UNDER MICROWAVE IRRADIATION[J].Speciality Petrochemicals,2007,24(1):29-31. |
| |
| Authors: | Lü Weizhong Liu Bo Wei Shaohui Wu Yiguang |
| |
| Affiliation: | College of Science, Shenzhen University, Shenzhen 518060, Guangdong , China |
| |
| Abstract: | 1-(p-Methoxybenzyl)-2-(p-methoxyphenzyl)-benzimidazole was synthesized by the reaction of o-phenylenediamine with p-methoxybenaldehyde under microwave irradiation with ethyl alcohol as solvent.The orthogonally designed experiments showed that the optimal reaction conditions were as follows:n(p-methoxybenaldehyde):n(o-phenylene diamine)=2.2:1,microwave irradiation 20 min and irradiation temperature 78℃.Under the optimal conditions,the highest yield of the title com- pound was about 40%.The samples synthesized were characterized by melting point determination, IR spectrum,~1H NMR spectra and ~(13)C NMR spectra. |
| |
| Keywords: | microwave irradiation benzimidazole orthogonally designed experiment characterization |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
