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Heteroaryl-substituted 4-(1H-pyrazol-1-yl)-5,6-dihydro-1H-pyrrolo[2,3-d]pyrimidine derivatives as potent and selective corticotropin-releasing factor receptor-1 antagonists |
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| Authors: | Sabbatini Fabio Maria Di Fabio Romano St-Denis Yves Capelli Anna-Maria Castiglioni Emiliano Contini Stefania Donati Daniele Fazzolari Elettra Gentile Gabriella Micheli Fabrizio Pavone Francesca Rinaldi Marilisa Pasquarello Alessandra Zampori Maria Grazia Di Felice Pina Zarantonello Paola Arban Roberto Perini Benedetta Vitulli Giovanni Benedetti Roberto Oliosi Beatrice Worby Angela |
| Affiliation: | Department of Medicinal Chemistry, Psychiatry Centre of Excellence for Drug Discovery (CEDD), Medicines Research Centre, GlaxoSmithKline SpA, Via A. Fleming 4, 37135 Verona, Italy. fabio.m.sabbatini@GSK.com |
| Abstract: | |
| Keywords: | anxiety corticotropin releasing factor CRF1 antagonists depression |
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