| 层状结构磷酸钙骨水泥组织工程支架材料的制备与表征 |
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| 引用本文： | 罗方聪,叶建东.层状结构磷酸钙骨水泥组织工程支架材料的制备与表征[J].硅酸盐通报,2009,28(1):27-30. |
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| 作者姓名： | 罗方聪 叶建东 |
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| 作者单位： | 华南理工大学特种功能材料教育部重点实验室,广州,510640;华南理工大学材料学院,广州,510640 |
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| 基金项目： | 国家自然科学基金，广东省自然科学基金 |
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| 摘 要： | 采用可溶粒子造孔法结合冷等静压成型技术,模拟扁骨的结构,制备了一种新型层状结构的多孔磷酸钙骨水泥组织工程支架材料,并用XRD和SEM等手段对其组成和结构进行了表征,用万能材料试验机测定了支架的抗压强度.结果表明,材料由致密层和多孔层构成,具有与扁骨类似的结构.其中致密层起到了增强作用,可以显著提高支架的强度.支架多孔层的孔隙率(77.26±1.99)%,孔隙直径在100～400 μm,决定于可溶盐晶粒的大小;致密层的孔隙率(20.78±0.56)%,主要是磷酸钙骨水泥固化过程中产生的微孔.
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| 关 键 词： | 磷酸钙骨水泥 组织工程支架 层状 多孔 |
Preparation and Characterization of Layered Porous Calcium Phosphate Cement Scaffold for Tissue Engineering |
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| LUO Fang-cong,YE Jian-dong.Preparation and Characterization of Layered Porous Calcium Phosphate Cement Scaffold for Tissue Engineering[J].Bulletin of the Chinese Ceramic Society,2009,28(1):27-30. |
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| Authors: | LUO Fang-cong YE Jian-dong |
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| Affiliation: | 1.Key Laboratory of Specially Functional Material;Ministry of Education;South China University of Technology;Guangzhou 510640;China;2.School of Material Science and Engineering;China |
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| Abstract: | A layered porous calcium phosphate cement (CPC) scaffold was prepared by a salt-leaching method and cold isostatic pressing molding technology,imitating the structure of the flat bone. The phase composition,microstructure and compressive strength of the layered porous scaffolds were evaluated by X-ray diffraction (XRD),scanning electron microscopy (SEM),and a universal testing machine. The results indicate that the layered scaffolds are composed of an inner porous CPC layer and outer compact CPC layers,whic... |
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| Keywords: | calcium phosphate cement scaffold for tissue engineering layered porous |
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