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Efficient synthesis of the key chiral alcohol intermediate of Crizotinib using dual-enzyme@CaHPO4 hybrid nanoflowers assembled by mimetic biomineralization |
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| Authors: | Xinxin Chen Liqing Xu Anming Wang Huimin Li Chenhui Wang Xiaolin Pei Pengfei Zhang Stephen G Wu |
| Affiliation: | 1. College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, P. R. China;2. Department of Energy, Environmental and Chemical Engineering, Washington University, St. Louis, MO, USA |
| Abstract: | |
| Keywords: | Crizotinib dual-enzyme@CaHPO4 hybrid nanoflowers chiral alcohol cascade reaction |