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Enzymatic synthesis of (R)- and (S)-2-cyclohepten-1-ol |
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| Authors: | Taeko Izumi Yuji Eda |
| Abstract: | The synthetically useful chiral synthons, (R)- and (S)-2-cyclohepten-1-ol, can be prepared by an enantioselective transesterification of racemic trans-2-(phenylseleno) cycloheptanol using lipases, followed by selenoxide elimination and hydrolysis. |
| Keywords: | (R)- and (S)-2-cyclohepten-1-ol porcine pancreatic lipase Pseudomonas cepacia lipase Candida cylindracea lipase Immobilized lipase from Pseudomonas sp |