Fast axonal transport rates are unchanged in 6- and 24-month F344 rats |
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| Authors: | JM Jacob |
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| Affiliation: | Department of Microbiology, College of Veterinary Medicine, Michigan State University, East Lansing 48824, USA. |
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| Abstract: | The maximum rate of fast axonal transport in motor axons at 6 and 24 months was measured in F344 rats. Tritiated proline was injected near sciatic motoneurons and rats were killed after 2-5 h. Nerves were processed for liquid scintillation spectroscopy and fast transport rates calculated. The rates, in 6- and 24-month rats, were 373 +/- 12 mm/day and 368 +/- 10 mm/day, respectively. Thus, the maximum fast transport rate is unchanged with age in F344 rats. |
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