Abstract: | Although it is frequently stated that the frontal lobes play a significant role in memory function, research proof has been ambiguous at best. The present study investigated this problem by administering a variety of memory tests (e.g., Wechsler Memory Scale, WAIS) to 16 schizophrenic patients who had undergone prefrontal leukotomy approximately 25 yrs earlier. Ss were divided into 3 groups on the basis of recovery after surgery. Two comparison groups (5 psychiatric and 5 normal controls) were established to control for psychiatric symptomatology, years of institutionalization, age, and years of education. Results indicate that large bilateral orbitofrontal lesions may not result in amnesia; in fact, the nonoperated schizophrenic control group performed the most poorly. Proactive interference was demonstrated, however, resulting in significant impairment for all Ss with prefrontal lobe damage despite normal scores on commonly used memory tests. Ability to maintain consistent and directed attention and to overcome interference is proposed as a role of the frontal lobes in memory function. (55 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) |