非汞电极溶出伏安法在药物及生物材料分析中的应用

综述了近十几年来国内外有关碳及其修饰电极、贵金属电极等非汞电极溶出伏安法在药物及生物材料分析中的应用情况：在生命科学的研究中，对于药物药理研究、参与生命活动的各种微量元素及活体组织中神经递质的检测与高灵敏的分析技术密不可分，而溶出伏安法是进行这些研究的最有效手段之一．与传统汞电极相比，非汞电极由于具有无污染、扫描电位广、易于修饰、能在复杂环境下取得电信号、利用微型电极便于活体检测等特点，因此发展十分迅速．但如何提高固体电极的重现性，不断完善微电极及超微电极用于伏安测定特别是活体分析，仍是今后所面临的课题之一．

THE APPLICATION OF STRIPPING VOLTAMMETRY IN THE DETERMINATION OF DRUG AND BIOLOGICAL SAMPLES WITH NON MERCURY ELECTRODES

The application of stripping voltammetry with non mercury electrodes to drug analysis and biological samples in the latest ten years is reviewed.The sensitive analytical methods have become a very important means of drug and biological research.The understanding of the changes of concentration of many endogenous and external substances which are present in complex biological samples are essential,therefore stripping voltammetry possessing high sensitivity is one of the most important tools.In comparison with the conventional mercury electrode,the main advantages of the non mercury electrode are improved its advances and practical applications.To raise the reproducibility of solid electrode,apply the improved micro electrode and super micro electrode to voltammetry measurement,especially somatometry are the tasks ahead.