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一类具有时滞的HIV感染模型的动力学性态
引用本文:邢青红,李 灿,马慧莲,郭尊光.一类具有时滞的HIV感染模型的动力学性态[J].工程数学学报,2022,39(5):750-762.
作者姓名:邢青红  李 灿  马慧莲  郭尊光
作者单位:太原工业学院理学系,太原030008
基金项目:山西省自然科学基金(201901D111322);太原工业学院青年(后备)学科带头人支持计划(201808);太原工业学院引进人才科研资助项目(2022KJ070).
摘    要:研究一类具有胞内时滞和饱和发生率的HIV感染动力学模型,通过计算得到了病毒感染的基本再生率。进而,通过分析特征方程根的分布,讨论了系统可行平衡点的局部渐近稳定性。根据构造的Lyapunov泛函,证明了当基本再生率小于1时,病毒未感染平衡点是全局渐近稳定的。利用无穷维动力系统的持续生存理论证明了当基本再生率大于1时,系统是一致持续生存的。最后,采用比较原理和单调迭代技巧,给出了病毒感染平衡点全局吸引的充分条件。

关 键 词:胞内时滞  饱和发生率  病毒感染的基本再生率  稳定性  

Dynamic Behavior of an HIV Infection Model with Intracellular Delay
XING Qinghong,LI Can,MA Huilian,GUO Zunguang.Dynamic Behavior of an HIV Infection Model with Intracellular Delay[J].Chinese Journal of Engineering Mathematics,2022,39(5):750-762.
Authors:XING Qinghong  LI Can  MA Huilian  GUO Zunguang
Affiliation:Department of Science, Taiyuan Institute of Technology, Taiyuan 030008
Abstract:An HIV infection dynamics model with intracellular delay is studied. The basic reproduction ratio is obtained by calculation. By analyzing the distribution of roots of the corresponding characteristic equations, the local stability of each of feasible equilibria is established. By constructing the suitable Lyapunov functional, it is proved that if the basic reproduction ratio is less than unity, the infection-free equilibrium is globally asymptotically stable. From the persistence theory of infinite dimensional dynamic system, it shows that if the basic reproduction ratio is greater than unity, the system is uniformly persistent. According to the iteration technique and comparision arguments, the sufficient conditions are obtained for the global attractivity of the chronic infection equilibrium.
Keywords:intracellular time delay  saturation incidence  the basic reproduction ratio  stability  
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