Comparative study of the essential oils of three Beilschmiedia species and their biological activities |
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| Authors: | Wan Mohd Nuzul Hakimi Wan Salleh Farediah Ahmad Heng Yen Khong Razauden Mohamed Zulkifli |
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| Affiliation: | 1. Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia (UTM), Skudai, Johor, Malaysia;2. School of Chemistry and Environmental Studies, Faculty of Applied Sciences, Universiti Teknologi MARA 3. (UiTM) Sarawak, Kota Samarahan, Sarawak, Malaysia;4. Department of Bioscience and Health Sciences, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia (UTM), Skudai, Johor, Malaysia |
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| Abstract: | This study was designed to examine the chemical compositions of the essential oils from three Beilschmiedia species and antioxidant, antimicrobial, antityrosinase, acetylcholinesterase and anti‐inflammatory activities. The essential oils of B. kunstleri, B. maingayi, B. penangiana gave β‐caryophyllene (10.6–12.1%), β‐eudesmol (17.5–24.1%) and δ‐cadinene (17.5–28.7%) as the most abundant components respectively. The bark oil of B. maingayi showed the highest activity in β‐carotene/linoleic acid (125.9%) and phenolic content (288.2 mg GA g?1), while B. penangiana bark oil was found to have strong activity in DPPH (IC50 84.7 μg mL?1) and ABTS (IC50 108.3 μg mL?1). The essential oils of B. penangiana showed the best activity against Candida glabrata with MIC value 31.3 μg mL?1. The bark oil of B. penangiana gave 82.5% tyrosinase inhibiton. The leaf oil of B. maingayi gave the highest inhibition in AChE (66.6%) and lipoxygenase (77.0%) assay. Our findings demonstrate that the essential oils have great potential for applications in pharmaceutical and food industries. |
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| Keywords: | Acetylcholinesterase anti‐inflammatory antimicrobial antioxidant antityrosinase Beilschmiedia essential oil |
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