Study of methods of inactivating a concentrated, purified cultured antirabies vaccine] |
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Authors: | DV Krutilina AV Dulina VM Morozova RS Mad'iarova EK Kovliasova |
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Abstract: | Two methods of inactivation, with ultraviolet (UV) and gamma (gamma) rays, of the concentrated purified tissue culture rabies vaccine from the Vnukovo-32 strain were studied. Under the optimal conditions of treatment of 100-fold concentrated purified virus-containing suspension, a completely inactivated vaccine with high immunogenicity indices (4.1 to 78) was obtained. Both the inactivation methods were found to be of equal value. |
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