| 用于生物组织层析成像的共聚焦内窥镜 |
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| 引用本文： | 刘勇,陈家璧.用于生物组织层析成像的共聚焦内窥镜[J].光学精密工程,2008,16(4):579-584. |
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| 作者姓名： | 刘勇 陈家璧 |
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| 作者单位： | 1. 肇庆学院,物理系,广东,肇庆,526061
2. 上海理工大学,光电学院,上海,200093 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | 为了获取生物组织的层析图像，建立了共聚焦内窥镜成像系统,对该系统的横向和轴向分辨能力进行测量和分析，并且对其在猪皮肤组织的层析成像能力进行研究。首先根据系统工作要求，说明系统的工作原理和组成结构，然后给出系统空间分辨能力的理论计算式，最后测试系统性能，说明测量值与理论值存在偏差的主要原因。实验结果表明：建立的系统轴向分辨能力约为10 ；横向分辨能力约为1.9 ；该系统可以对猪皮肤组织进行层析成像。
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| 关 键 词： | 层析成像 生物组织 共聚焦内窥镜 |
| 文章编号： | 1004-924X(2008)04-0579-06 |
| 收稿时间： | 2007-11-16 |
| 修稿时间： | 2007年11月16 |
Tomographic imaging of tissue using confocal endoscope |
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| LIU Yong,CHEN Jia-bi.Tomographic imaging of tissue using confocal endoscope[J].Optics and Precision Engineering,2008,16(4):579-584. |
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| Authors: | LIU Yong CHEN Jia-bi |
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| Abstract: | In order to obtain tomographic image of tissue, a confocal endscopic imaging system is established, its axial and lateral resolution has been measured and analyzed, and its application in pig skin has been investigated. First, based on the requirement of system, principles and configuration of system are presented. Then the theoretical values of spatial resolution are shown in confcoal endoscope. Finally, the system is tested, and the reason for difference between measuring date and theoretical value is illuminated. Experimental results indicate that its axial and lateral resolution is respectively 10 and 1.9 , and it can be used to obtained tomographic image in pig skin. |
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