Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme factor Xa |
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| Authors: | GB Phillips BO Buckman DD Davey KA Eagen WJ Guilford J Hinchman E Ho S Koovakkat A Liang DR Light R Mohan HP Ng JM Post KJ Shaw D Smith B Subramanyam ME Sullivan L Trinh R Vergona J Walters K White M Whitlow S Wu W Xu MM Morrissey |
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| Affiliation: | Discovery Research, Berlex Biosciences, 15049 San Pablo Avenue, P.O. Box 4099, Richmond, California 94804-0099, USA. |
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