| 魔芋葡甘聚糖硫酸酯的制备及其体外抗凝血活性研究 |
| |
| 引用本文： | 朱焱,谭占鳌,史亚君. 魔芋葡甘聚糖硫酸酯的制备及其体外抗凝血活性研究[J]. 武汉理工大学学报(信息与管理工程版), 2005, 27(1): 150-153 |
| |
| 作者姓名： | 朱焱 谭占鳌 史亚君 |
| |
| 作者单位： | 1. 武汉理工大学,化学工程学院,湖北,武汉,430070
2. 宁波教育学院,浙江,宁波,315000 |
| |
| 摘 要： | 以魔芋精粉为原料,在N,N-二甲基甲酰胺(DMF)介质中通过磺化反应成功制备出魔芋葡甘聚糖硫酸酯;以元素分析、红外光谱及激光光散射-尺寸排除色谱联用仪研究了其结构,并用体外凝血试验测定了目标化合物活化部分的凝血活酶时间APTT(Activatedpartialthrombintime)、凝血酶时间TT(Thrombintime)和凝血酶原时间PT(Prothrombintime),同时,探讨了魔芋葡甘聚糖硫酸酯的取代度DS(Degreeofsubstitution)与抗凝血活性的关系。
|
| 关 键 词： | 魔芋葡甘聚糖 魔芋葡甘聚糖硫酸酯 抗凝血活性 |
| 文章编号： | 1007-144X(2005)01-0150-04 |
| 修稿时间： | 2004-10-11 |
Preparation and Anticoagulant in Vitro Activities of Konjac Glucomannan Sulfate |
| |
| Zhu Yan,Tan Zhan'ao,Shi Yajun Zhu Yan: Lect, School of Chemical Engineering,WUT,Wuhan ,China.. Preparation and Anticoagulant in Vitro Activities of Konjac Glucomannan Sulfate[J]. Journal of Wuhan University of Technology(Information & Management Engineering), 2005, 27(1): 150-153 |
| |
| Authors: | Zhu Yan Tan Zhan'ao Shi Yajun Zhu Yan: Lect School of Chemical Engineering WUT Wuhan China. |
| |
| Affiliation: | Zhu Yan,Tan Zhan'ao,Shi Yajun Zhu Yan: Lect, School of Chemical Engineering,WUT,Wuhan 430070,China. |
| |
| Abstract: | Konjac Glucomannan Sulfate (KGMS) with different Degrees of Substitution (DS) is prepared from Konjac flour. The structure of the derivatives is characterized by element analysis. Activated Partial Thromboplastin Time (APTT), Throbin Time (TT) and Prothrombin Time (PT) are tested. The relationship between the Degree of Substitution (DS) and anticoagulant activity is discussed. |
| |
| Keywords: | konjac glucomannan konjac glucomannan sulfate anticoagulant activity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
